Assay Detail
Functional
CHEMBL4158938
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Cytotoxicity against imatinib-resistant human KCL22 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KCL-22 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.53 | 5.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167623 | — | — | 1 | 5.59 |
| CHEMBL2364628 | RICOLINOSTAT | 2.0 | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167623 | — | IC50 | = | 2580.0 | nM | 5.59 |
| CHEMBL2364628 | RICOLINOSTAT | IC50 | = | 3380.0 | nM | 5.47 |