Assay Detail
Functional
CHEMBL4178201
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Antiparasitic activity against Toxoplasma gondii after 4 days by chlorophenol red-beta-D-galactosidase based assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Recent developments in drug discovery against the protozoal parasites Cryptosporidium and Toxoplasma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.71 | 6.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL310555 | OXYQUINOLINE | -1.0 | 1 | 6.67 |
| CHEMBL4213697 | — | — | 1 | 6.37 |
| CHEMBL14474 | QUINOLINE | — | 1 | 5.30 |
| CHEMBL4207687 | — | — | 1 | 5.30 |
| CHEMBL164449 | — | — | 1 | 5.30 |
| CHEMBL2042580 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL310555 | OXYQUINOLINE | IC50 | = | 213.0 | nM | 6.67 |
| CHEMBL4213697 | — | IC50 | = | 425.0 | nM | 6.37 |
| CHEMBL14474 | QUINOLINE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4207687 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL164449 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2042580 | — | IC50 | = | 5000.0 | nM | 5.30 |