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Assay Detail

CHEMBL4178539

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human HeLa cells incubated for 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium.
Iwasaki A, Tadenuma T, Sumimoto S, Ohshiro T, Ozaki K, Kobayashi K, Teruya T, Tomoda H, Suenaga K.
J Nat Prod (2017) 80 : 1161 -1166
PubMed 28294609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.75 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4207391 1 5.35
CHEMBL4212280 1 4.54
CHEMBL4207917 1 4.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4207391 IC50 = 4500.0 nM 5.35
CHEMBL4212280 IC50 = 29000.0 nM 4.54
CHEMBL4207917 IC50 = 43000.0 nM 4.37