Assay Detail
Functional
CHEMBL4178693
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of fMLP/CB-induced superoxide anion production in human neutrophils assessed as SOD-based ferricytochrome c reduction assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Neutrophil |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-inflammatory Flavan-3-ol-dihydroretrochalcones from Daemonorops draco.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.93 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98350 | LY-294002 | -1.0 | 1 | 6.40 |
| CHEMBL4217625 | — | — | 1 | 5.89 |
| CHEMBL4206864 | — | — | 1 | 5.51 |
| CHEMBL4210279 | — | — | 1 | - |
| CHEMBL4205386 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98350 | LY-294002 | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL4217625 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4206864 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4210279 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4205386 | — | IC50 | > | 10000.0 | nM | - |