Assay Detail
Functional
CHEMBL4178849
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Antiviral activity against Chikungunya virus LR2006-OPY1 infected in BHK21 cells after 48 hrs by luciferase reporter gene assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The medicinal chemistry of Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.75 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4082099 | — | — | 1 | 6.22 |
| CHEMBL4217232 | — | — | 1 | 5.82 |
| CHEMBL295124 | BERBERINE | 4.0 | 1 | 5.75 |
| CHEMBL7301 | FENRETINIDE | 3.0 | 1 | 5.51 |
| CHEMBL4206476 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4082099 | — | EC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4217232 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL295124 | BERBERINE | EC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL7301 | FENRETINIDE | EC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4206476 | — | EC50 | = | 3700.0 | nM | 5.43 |