Assay Detail
Functional
CHEMBL4178850
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Chikungunya virus LR2006-OPY1 infected in human Huh7.5 cells after 48 hrs by luciferase reporter gene assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The medicinal chemistry of Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.89 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7301 | FENRETINIDE | 3.0 | 1 | 6.30 |
| CHEMBL4206476 | — | — | 1 | 5.85 |
| CHEMBL4217232 | — | — | 1 | 5.85 |
| CHEMBL295124 | BERBERINE | 4.0 | 1 | 5.72 |
| CHEMBL4082099 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7301 | FENRETINIDE | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4206476 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4217232 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL295124 | BERBERINE | EC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4082099 | — | EC50 | = | 1900.0 | nM | 5.72 |