Assay Detail
Functional
CHEMBL4178857
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Antiviral activity against Chikungunya virus MY/065/08/FN295485 infected in African green monkey Vero cells assessed as reduction in virus yield after 48 hrs by titration assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The medicinal chemistry of Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.85 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL485818 | BAICALIN | — | 1 | 5.16 |
| CHEMBL31574 | FISETIN | 2.0 | 1 | 4.53 |
| CHEMBL413552 | QUERCETAGETIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL485818 | BAICALIN | IC50 | = | 6997.0 | nM | 5.16 |
| CHEMBL31574 | FISETIN | IC50 | = | 29500.0 | nM | 4.53 |
| CHEMBL413552 | QUERCETAGETIN | IC50 | = | 25300000.0 | nM | - |