Assay Detail
Functional
CHEMBL4178864
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Antiviral activity against Chikungunya virus 899 infected in African green monkey Vero A cells assessed as inhibition of virus-induced cytopathogenic effect measured on day 5 post infection by MTS/PMS based microscopic analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The medicinal chemistry of Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.21 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4216574 | — | — | 1 | 5.40 |
| CHEMBL4212128 | — | — | 1 | 5.12 |
| CHEMBL4211601 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4216574 | — | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL4212128 | — | EC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL4211601 | — | EC50 | = | 8000.0 | nM | 5.10 |