Assay Detail
Binding
CHEMBL4179920
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of sodium channel site2 (unknown origin) by radioligand binding assay relative to control
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.32 | 7.32 |
| Ki | 1 | 7.37 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217988 | — | — | 2 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217988 | — | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL4217988 | — | IC50 | = | 48.0 | nM | 7.32 |