Assay Detail
Binding
CHEMBL4181676
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum FP2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Cysteine protease falcipain-2 (CHEMBL5801) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.72 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1939368 | — | — | 1 | 5.16 |
| CHEMBL549325 | — | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1939368 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL549325 | — | IC50 | = | 54200.0 | nM | 4.27 |