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Assay Detail

CHEMBL4182537

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-biofilm activity against Pseudoalteromonas ulvae TC14 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Pseudoalteromonas ulvae
Confidence 1 — Organism
Curated By Intermediate

Target

Pseudoalteromonas ulvae (CHEMBL4296595)
Type ORGANISM
Organism Pseudoalteromonas ulvae

Publication

Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria.
Sall C, Ayé M, Bottzeck O, Praud A, Blache Y.
Bioorg Med Chem Lett (2018) 28 : 155 -159
PubMed 29198862 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 10 4.48 5.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL174 AMPICILLIN 4.0 1 5.03
CHEMBL4203012 1 4.95
CHEMBL4208085 1 4.94
CHEMBL4208238 1 4.28
CHEMBL4209185 1 4.26
CHEMBL4211217 1 4.13
CHEMBL64286 N-P-COUMAROYL TYRAMINE 1 4.12
CHEMBL4214226 1 4.09
CHEMBL4202823 1 -
CHEMBL4217069 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL174 AMPICILLIN EC50 = 9300.0 nM 5.03
CHEMBL4203012 EC50 = 11300.0 nM 4.95
CHEMBL4208085 EC50 = 11400.0 nM 4.94
CHEMBL4208238 EC50 = 52300.0 nM 4.28
CHEMBL4209185 EC50 = 54600.0 nM 4.26
CHEMBL4211217 EC50 = 73700.0 nM 4.13
CHEMBL64286 N-P-COUMAROYL TYRAMINE EC50 = 75500.0 nM 4.12
CHEMBL4214226 EC50 = 80600.0 nM 4.09
CHEMBL4202823 EC50 = 204300.0 nM -
CHEMBL4217069 EC50 = 115300.0 nM -