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Assay Detail

CHEMBL4184939

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to arginase 1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Arginase-1 (CHEMBL1075097)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small molecule immuno-oncology therapeutic agents.
Toogood PL.
Bioorg Med Chem Lett (2018) 28 : 319 -329
PubMed 29326017 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.33 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1234777 NOR-NOHA 1.0 1 7.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1234777 NOR-NOHA Kd = 47.0 nM 7.33