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Assay Detail

CHEMBL4184980

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Plasmodium falciparum FcB1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Design, synthesis and anti-malarial activities of synthetic analogs of biselyngbyolide B, a Ca<sup>2+</sup> pump inhibitor from marine cyanobacteria.
Sato E, Morita M, Ogawa H, Iwatsuki M, Hokari R, Ishiyama A, Ōmura S, Iwasaki A, Suenaga K.
Bioorg Med Chem Lett (2018) 28 : 298 -301
PubMed 29292225 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.31 5.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL480627 CYCLOPIAZONIC ACID 1 5.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL480627 CYCLOPIAZONIC ACID IC50 = 4900.0 nM 5.31