Assay Detail
Functional
CHEMBL4185232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against amastigote stage of Leishmania infantum infected in PMA-differentiated human THP-1 cells after 3 days by luciferase assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Cell Type | THP-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4211052 | — | — | 1 | 6.00 |
| CHEMBL4204117 | — | — | 1 | 6.00 |
| CHEMBL4215363 | — | — | 1 | 6.00 |
| CHEMBL4206570 | — | — | 1 | 6.00 |
| CHEMBL4211460 | — | — | 1 | 6.00 |
| CHEMBL4214749 | — | — | 1 | 6.00 |
| CHEMBL4209842 | — | — | 1 | 6.00 |
| CHEMBL4217062 | — | — | 1 | 6.00 |
| CHEMBL4205463 | — | — | 1 | 6.00 |
| CHEMBL4205986 | — | — | 1 | 6.00 |
| CHEMBL4217704 | — | — | 1 | 6.00 |
| CHEMBL4218232 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4211052 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4204117 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4215363 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4206570 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4211460 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4214749 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4209842 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4217062 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4205463 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4205986 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4217704 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4218232 | — | IC50 | = | 1000.0 | nM | 6.00 |