Assay Detail
Functional
CHEMBL4185237
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Antiparasitic activity against tachyzoite stage of Toxoplasma gondii
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.14 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96051 | SCRIPTAID | — | 1 | 7.41 |
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 7.39 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.08 |
| CHEMBL320497 | SUBEROHYDROXAMIC ACID | — | 1 | 6.67 |
| CHEMBL1140 | NIACINAMIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96051 | SCRIPTAID | IC50 | = | 39.0 | nM | 7.41 |
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL320497 | SUBEROHYDROXAMIC ACID | IC50 | = | 213.0 | nM | 6.67 |
| CHEMBL1140 | NIACINAMIDE | IC50 | = | 50000000.0 | nM | - |