Assay Detail
Functional
CHEMBL4185496
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Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by alamarBlue assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis and biological evaluation of fucose-truncated monosaccharide analogues of ipomoeassin F.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.62 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4163767 | — | — | 1 | 8.19 |
| CHEMBL4208625 | — | — | 1 | 7.78 |
| CHEMBL4213561 | — | — | 1 | 6.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4163767 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL4208625 | — | IC50 | = | 16.5 | nM | 7.78 |
| CHEMBL4213561 | — | IC50 | = | 131.0 | nM | 6.88 |