Assay Detail
ADMET
CHEMBL4185630
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Displacement of [3H]resveratrol from Sprague-Dawley rat brain plasma membranes after 1 hr by beta counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | plasma membranes |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.40 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36327 | EPICATECHIN GALLATE | — | 1 | 7.60 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | 3.0 | 1 | 7.60 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 6.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36327 | EPICATECHIN GALLATE | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL165 | RESVERATROL | Ki | = | 102.0 | nM | 6.99 |