Assay Detail
ADMET
CHEMBL4186141
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Inhibition of MMP14 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.28 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4208519 | — | — | 1 | 5.36 |
| CHEMBL4215407 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4208519 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL4215407 | — | IC50 | = | 6500.0 | nM | 5.19 |