Assay Detail
Binding
CHEMBL4187629
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using varying CMNPC substrate levels by fluorescence based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.41 | 8.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4216368 | — | — | 1 | 8.04 |
| CHEMBL4215208 | — | — | 1 | 7.37 |
| CHEMBL2397148 | — | — | 1 | 6.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4216368 | — | Ki | = | 9.1 | nM | 8.04 |
| CHEMBL4215208 | — | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL2397148 | — | Ki | = | 156.0 | nM | 6.81 |