Assay Detail
Binding
CHEMBL4187647
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Inhibition of soluble epoxide in horse brain microsomes using CMNPC substrate by fluorescence based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Equus caballus |
| Tissue | Brain |
| Subcellular | microsomes |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.50 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2397148 | — | — | 1 | 7.72 |
| CHEMBL4216368 | — | — | 1 | 7.68 |
| CHEMBL4215208 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2397148 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL4216368 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL4215208 | — | IC50 | = | 77.0 | nM | 7.11 |