Assay Detail
Functional
CHEMBL4188130
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Growth inhibition of human A549 cells incubated for 6 days in presence of 400 U/ml IFNalpha by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.77 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217121 | — | — | 1 | 4.96 |
| CHEMBL4206466 | — | — | 1 | 4.77 |
| CHEMBL4218471 | — | — | 1 | 4.57 |
| CHEMBL4215246 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217121 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4206466 | — | EC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL4218471 | — | EC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL4215246 | — | EC50 | > | 40000.0 | nM | - |