Assay Detail
Binding
CHEMBL4188512
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant His-tagged MIF tautomerase activity (unknown origin) using 4-HPP as substrate pretreated for 2 mins followed by substrate addition
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Macrophage migration inhibitory factor (CHEMBL2085) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.87 | 4.87 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4204904 | — | — | 1 | 4.87 |
| CHEMBL4207747 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4204904 | — | IC50 | = | 13500.0 | nM | 4.87 |
| CHEMBL4207747 | — | Inhibition | - | % | - |