Assay Detail
Functional
CHEMBL4189249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
3
Total Activities
1
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| IC50 | 1 | 5.41 | 5.41 |
| IC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4207458 | — | — | 3 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4207458 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL4207458 | — | Activity | - | — | - | |
| CHEMBL4207458 | — | IC90 | = | 16400.0 | nM | - |