Assay Detail
Binding
CHEMBL4190519
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to HPV 18 CCTGG TATTAGTCAT TTTCC LCR DNA (7606 to 7615 nucleotides) after 4 hrs by DNase I footprinting assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human papillomavirus type 18 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus <i>Via</i> N-Terminal Guanidinium Substitution.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.99 | 9.05 |
| Activity | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217480 | — | — | 2 | 9.05 |
| CHEMBL4213066 | — | — | 2 | 9.00 |
| CHEMBL4205776 | — | — | 2 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217480 | — | Kd | = | 0.9 | nM | 9.05 |
| CHEMBL4213066 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL4205776 | — | Kd | = | 1.2 | nM | 8.92 |
| CHEMBL4217480 | — | Activity | - | — | - | |
| CHEMBL4205776 | — | Activity | - | — | - | |
| CHEMBL4213066 | — | Activity | - | — | - |