Assay Detail
Binding
CHEMBL4190520
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Binding affinity to HPV 18 ACATA TTTTGAACAA TTGGC LCR DNA (7559 to 7568 nucleotides) after 4 hrs by DNase I footprinting assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human papillomavirus type 18 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus <i>Via</i> N-Terminal Guanidinium Substitution.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.00 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217480 | — | — | 1 | 9.05 |
| CHEMBL4213066 | — | — | 1 | 9.00 |
| CHEMBL4205776 | — | — | 1 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217480 | — | Kd | = | 0.9 | nM | 9.05 |
| CHEMBL4213066 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL4205776 | — | Kd | = | 1.1 | nM | 8.96 |