Assay Detail
Binding
CHEMBL4190540
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant human His-tagged EP300 expressed in bacterial expression system by isothermal titration calorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical probes and inhibitors of bromodomains outside the BET family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.98 | 7.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3622373 | — | — | 1 | 7.50 |
| CHEMBL3753333 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3622373 | — | Kd | = | 32.0 | nM | 7.50 |
| CHEMBL3753333 | — | Kd | = | 350.0 | nM | 6.46 |