Assay Detail
Binding
CHEMBL4190545
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to C-terminally biotinylated N-terminal His10-tagged human CBP bromodomain (R1081 to G1198 residues) expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical probes and inhibitors of bromodomains outside the BET family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.82 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3774655 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3774655 | — | Kd | = | 151.0 | nM | 6.82 |