Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4193405

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in human type A+ erythrocytes after 48 hrs by [3H]-hypoxanthine incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Quinoline hybrids and their antiplasmodial and antimalarial activities.
Hu YQ, Gao C, Zhang S, Xu L, Xu Z, Feng LS, Wu X, Zhao F.
Eur J Med Chem (2017) 139 : 22 -47
PubMed 28800458 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4218834 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4218834 IC50 = 10.0 nM 8.00