Assay Detail
Functional
CHEMBL4193415
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Antimalarial activity against chloroquine-resistant Plasmodium falciparum D6 infected in erythrocytes by [3H]-hypoxanthine incorporation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Quinoline hybrids and their antiplasmodial and antimalarial activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.56 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL343320 | — | — | 1 | 8.92 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 8.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL343320 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 6.5 | nM | 8.19 |