Assay Detail
Functional
CHEMBL4193441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against synchronous culture of Plasmodium falciparum W2 ring stage infected in human erythrocytes after 48 hrs by flow cytometry
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Quinoline hybrids and their antiplasmodial and antimalarial activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2316519 | — | — | 1 | 7.96 |
| CHEMBL2316520 | — | — | 1 | 7.96 |
| CHEMBL2316521 | — | — | 1 | 7.96 |
| CHEMBL2316522 | — | — | 1 | 7.96 |
| CHEMBL2316795 | — | — | 1 | 7.96 |
| CHEMBL2316797 | — | — | 1 | 7.96 |
| CHEMBL2316796 | — | — | 1 | 7.96 |
| CHEMBL2316798 | — | — | 1 | 7.96 |
| CHEMBL2316799 | — | — | 1 | 7.96 |
| CHEMBL2316802 | — | — | 1 | 7.96 |
| CHEMBL2316801 | — | — | 1 | 7.96 |
| CHEMBL2316800 | — | — | 1 | 7.96 |
| CHEMBL2316803 | — | — | 1 | 7.96 |
| CHEMBL2316804 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2316519 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316520 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316521 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316522 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316795 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316797 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316796 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316798 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316799 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316802 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316801 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316800 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316803 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2316804 | — | IC50 | = | 11.0 | nM | 7.96 |