Assay Detail
ADMET
CHEMBL4193673
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Cytotoxicity against human Ishikawa cells after 96 hrs by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | Ishikawa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.90 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | 2.0 | 1 | 5.38 |
| CHEMBL376915 | — | — | 1 | 4.72 |
| CHEMBL492828 | ISOXANTHOHUMOL | — | 1 | 4.60 |
| CHEMBL294099 | — | — | 1 | - |
| CHEMBL135 | ESTRADIOL | 4.0 | 1 | - |
| CHEMBL1537093 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL376915 | — | IC50 | = | 19100.0 | nM | 4.72 |
| CHEMBL492828 | ISOXANTHOHUMOL | IC50 | = | 24900.0 | nM | 4.60 |
| CHEMBL294099 | — | IC50 | - | — | - | |
| CHEMBL135 | ESTRADIOL | IC50 | - | — | - | |
| CHEMBL1537093 | — | IC50 | > | 5000.0 | nM | - |