Assay Detail
Functional
CHEMBL4193712
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human IMR5 cells expressing TP53 after 48 hrs by CellTiter96 AQueous one solution cell proliferation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | IMR-5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.24 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4208780 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4208780 | — | EC50 | = | 5800.0 | nM | 5.24 |