Assay Detail
Binding
CHEMBL4194795
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Competitive inhibition of aminopeptidase-M (unknown origin)
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.40 | 7.72 |
| IC50 | 1 | 6.40 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4205440 | — | — | 1 | 7.72 |
| CHEMBL4217873 | — | — | 1 | 7.72 |
| CHEMBL308333 | ACTINONIN | — | 2 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4205440 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL4217873 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL308333 | ACTINONIN | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL308333 | ACTINONIN | IC50 | = | 400.0 | nM | 6.40 |