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Assay Detail

CHEMBL4194805

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of LAP in porcine kidney microsomes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Tissue Kidney
Subcellular microsomes
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Leucine aminopeptidase (CHEMBL3763002)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.
Amin SA, Adhikari N, Jha T.
J Med Chem (2018) 61 : 6468 -6490
PubMed 29630364 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.66 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69349 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69349 Ki = 22.0 nM 7.66