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Assay Detail

CHEMBL4196323

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human trypsin using S-2222 as substrate after 30 mins by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Intermediate

Target

Trypsin (CHEMBL2095204)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

The selectivity and bioavailability improvement of novel oral anticoagulants: An overview.
Xie Z, Tian Y, Lv X, Xiao X, Zhan M, Cheng K, Li S, Liao C.
Eur J Med Chem (2018) 146 : 299 -317
PubMed 29407959 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.80 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL37251 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL37251 Ki = 16.0 nM 7.80