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Assay Detail

CHEMBL4197924

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Functional
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in red blood cells assessed as reduction in mature schizonts formation after 72 hrs by Giemsa-staining based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Pyrazole-pyrazoline as promising novel antimalarial agents: A mechanistic study.
Kumar G, Tanwar O, Kumar J, Akhter M, Sharma S, Pillai CR, Alam MM, Zama MS.
Eur J Med Chem (2018) 149 : 139 -147
PubMed 29499486 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL116847 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL116847 IC50 = 69.0 nM 7.16