Assay Detail
Functional
CHEMBL4197972
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Antiviral activity against Dengue virus 3 infected in African green monkey Vero cells assessed as decrease in viral infection preincubated for 1 hr followed by cell addition and subsequent incubation for 1 hr and measured after 5 to 6 days by crystal violet staining-based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 3 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.21 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL83598 | — | — | 1 | 5.74 |
| CHEMBL3275868 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL83598 | — | EC50 | = | 1820.0 | nM | 5.74 |
| CHEMBL3275868 | — | EC50 | = | 21000.0 | nM | 4.68 |