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Assay Detail

CHEMBL4198255

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MDA435 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-435
Confidence 1 — Organism
Curated By Intermediate

Target

MDA-MB-435 (CHEMBL614697)
Type CELL-LINE
Organism Homo sapiens

Publication

Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms.
Dadashpour S, Emami S.
Eur J Med Chem (2018) 150 : 9 -29
PubMed 29505935 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.82 9.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL56157 1 9.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL56157 IC50 = 0.15 nM 9.82