Assay Detail
Functional
CHEMBL4198591
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Antiviral activity against HBV
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Polypharmacology in HIV inhibition: can a drug with simultaneous action against two relevant targets be an alternative to combination therapy?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.02 | 6.52 |
| IC50 | 1 | 6.16 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298845 | — | — | 1 | 6.52 |
| CHEMBL484 | ADEFOVIR | 3.0 | 1 | 6.16 |
| CHEMBL4206022 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298845 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL484 | ADEFOVIR | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL4206022 | — | EC50 | = | 3100.0 | nM | 5.51 |