Assay Detail
Binding
CHEMBL4199258
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GSTO1-1 (unknown origin) by 4-NPG substrate based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.08 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4203414 | — | — | 1 | 7.40 |
| CHEMBL1598561 | — | — | 1 | 6.92 |
| CHEMBL414890 | PROTOAPIGENONE | — | 1 | 5.80 |
| CHEMBL484853 | CARNOSIC ACID | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4203414 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1598561 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL414890 | PROTOAPIGENONE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL484853 | CARNOSIC ACID | IC50 | = | 62000.0 | nM | 4.21 |