Assay Detail
Binding
CHEMBL4199280
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes by Cheng-Prusoff equation analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.87 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4216263 | — | — | 1 | 8.22 |
| CHEMBL4204595 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4216263 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL4204595 | — | Ki | = | 30.0 | nM | 7.52 |