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Assay Detail

CHEMBL4199289

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of trypsin (unknown origin) using Chromozyme-TRY substrate incubated for 3 mins by spectrophotometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Intermediate

Target

Trypsin (CHEMBL2095204)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Factor XIa Inhibitors as New Anticoagulants.
Quan ML, Pinto DJP, Smallheer JM, Ewing WR, Rossi KA, Luettgen JM, Seiffert DA, Wexler RR.
J Med Chem (2018) 61 : 7425 -7447
PubMed 29775297 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL71037 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL71037 IC50 = 50.0 nM 7.30