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Assay Detail

CHEMBL4199308

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition recombinant human biotin-labeled MIF binding to recombinant human soluble CD47 receptor (73 to 232 residues) preincubated for 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Macrophage migration inhibitory factor (CHEMBL2085)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor.
Trivedi-Parmar V, Jorgensen WL.
J Med Chem (2018) 61 : 8104 -8119
PubMed 29812929 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.09 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296966 CHICAGO SKY BLUE SODIUM 1 6.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296966 CHICAGO SKY BLUE SODIUM IC50 = 810.0 nM 6.09