Assay Detail
Binding
CHEMBL4199355
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Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of β-Arrestin Biased Ligands of 5-HT7R.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.52 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4215875 | — | — | 1 | 7.70 |
| CHEMBL4209274 | — | — | 1 | 6.70 |
| CHEMBL4210782 | — | — | 1 | 6.53 |
| CHEMBL4218672 | — | — | 1 | 6.11 |
| CHEMBL4207884 | — | — | 1 | 6.10 |
| CHEMBL4218801 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4215875 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL4209274 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL4210782 | — | Ki | = | 296.0 | nM | 6.53 |
| CHEMBL4218672 | — | Ki | = | 785.0 | nM | 6.11 |
| CHEMBL4207884 | — | Ki | = | 799.0 | nM | 6.10 |
| CHEMBL4218801 | — | Ki | = | 1099.0 | nM | 5.96 |