Assay Detail
Functional
CHEMBL4200145
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Immunosuppressive activity in C57BL/6 mouse T cells assessed as inhibition of ConA-induced cell proliferation by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Murine T-cell line |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Alkaloids with Immunosuppressive Activity from the Bark of Pausinystalia yohimbe.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.67 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4216525 | — | — | 1 | 4.78 |
| CHEMBL31410 | CORYNANTHEINE | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4216525 | — | IC50 | = | 16800.0 | nM | 4.78 |
| CHEMBL31410 | CORYNANTHEINE | IC50 | = | 27600.0 | nM | 4.56 |