Assay Detail
Functional
CHEMBL4200270
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Antileishmanial activity against stationary-phase Leishmania amazonensis MHOM/BR/75/LTB0016 promastigotes infected in human THP1-derived macrophages at test compound to miltefosine ratio of 1:4 by serial dilution based light microscopic method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Efficacy of Apigenin and Miltefosine Combination Therapy against Experimental Cutaneous Leishmaniasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.80 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28 | APIGENIN | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28 | APIGENIN | EC50 | = | 160.0 | nM | 6.80 |