Assay Detail
Functional
CHEMBL4200306
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay
16
Total Activities
16
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LoVo |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antitumor Activity of Diterpenoids from Jatropha gossypiifolia: Cell Cycle Arrest and Apoptosis-Inducing Activity in RKO Colon Cancer Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| GI | 13 | - | - |
| IC50 | 3 | 4.84 | 4.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.94 |
| CHEMBL4213396 | — | — | 1 | 4.84 |
| CHEMBL2402276 | JATROPHONE | — | 1 | 4.73 |
| CHEMBL4217960 | — | — | 1 | - |
| CHEMBL4206244 | — | — | 1 | - |
| CHEMBL4217375 | — | — | 1 | - |
| CHEMBL4212423 | — | — | 1 | - |
| CHEMBL4212957 | — | — | 1 | - |
| CHEMBL4208050 | — | — | 1 | - |
| CHEMBL4209519 | — | — | 1 | - |
| CHEMBL4204661 | — | — | 1 | - |
| CHEMBL4205145 | — | — | 1 | - |
| CHEMBL4216848 | — | — | 1 | - |
| CHEMBL4210105 | — | — | 1 | - |
| CHEMBL4215026 | — | — | 1 | - |
| CHEMBL4214497 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL4213396 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL2402276 | JATROPHONE | IC50 | = | 18600.0 | nM | 4.73 |
| CHEMBL4217960 | — | GI | - | — | - | |
| CHEMBL4206244 | — | GI | - | — | - | |
| CHEMBL4217375 | — | GI | - | — | - | |
| CHEMBL4212423 | — | GI | - | — | - | |
| CHEMBL4212957 | — | GI | - | — | - | |
| CHEMBL4208050 | — | GI | - | — | - | |
| CHEMBL4209519 | — | GI | - | — | - | |
| CHEMBL4204661 | — | GI | - | — | - | |
| CHEMBL4205145 | — | GI | - | — | - | |
| CHEMBL4216848 | — | GI | - | — | - | |
| CHEMBL4210105 | — | GI | - | — | - | |
| CHEMBL4215026 | — | GI | - | — | - | |
| CHEMBL4214497 | — | GI | - | — | - |