Assay Detail
Functional
CHEMBL4201407
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Growth inhibition of Plasmodium falciparum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.19 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1922604 | — | — | 1 | 7.05 |
| CHEMBL2164257 | FOSMIDOMYCIN SODIUM | — | 1 | 7.05 |
| CHEMBL4206002 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1922604 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL2164257 | FOSMIDOMYCIN SODIUM | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL4206002 | — | IC50 | = | 33200.0 | nM | 4.48 |