Assay Detail
Functional
CHEMBL4201445
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Antiviral activity against oseltamivir-resistant Influenza A virus (H1N1) LN/1109
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus (H1N1) |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.01 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4206744 | — | — | 1 | 5.36 |
| CHEMBL1229 | OSELTAMIVIR | 4.0 | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4206744 | — | EC50 | = | 4360.0 | nM | 5.36 |
| CHEMBL1229 | OSELTAMIVIR | EC50 | = | 21700.0 | nM | 4.66 |