Assay Detail
Binding
CHEMBL4201613
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Displacement of DY647 from SNAP-tagged V1A receptor (unknown origin) expressed in HEK293 cells by TR-FRET assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.90 | 7.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3763342 | — | — | 1 | 7.90 |
| CHEMBL4217872 | — | — | 1 | 7.09 |
| CHEMBL360648 | — | — | 1 | 6.71 |
| CHEMBL4204210 | — | — | 1 | 5.90 |
| CHEMBL4216174 | — | — | 1 | - |
| CHEMBL4203314 | — | — | 1 | - |
| CHEMBL4212928 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3763342 | — | Ki | = | 12.5 | nM | 7.90 |
| CHEMBL4217872 | — | Ki | = | 82.0 | nM | 7.09 |
| CHEMBL360648 | — | Ki | = | 196.0 | nM | 6.71 |
| CHEMBL4204210 | — | Ki | = | 1253.0 | nM | 5.90 |
| CHEMBL4216174 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL4203314 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL4212928 | — | Ki | > | 1000.0 | nM | - |